Das Universitätsklinikum Augsburg ist Teil des GBA-Innovationsfondprojekt B(e)NAMSE:

­Ein Projekt zur Verbesserung der medizinischen und psychosozialen Versorgung von jungen Menschen mit Seltenen Erkrankungen.

Folgende Typ B-Zentren sind beteiligt:

• Zentrum für seltene Endokrinopathien | Kinder und Erwachsene 
• Zentrum für Tumordispositionssyndrome (ZeKiTDS) | Kinder und Erwachsene
• Zentrum für seltene neurologische Erkrankungen | Kinder
• Zentrum für seltene Nierenerkrankungen | Kinder

Weitere Informationen finden Sie hier: https://www.benamse.de/

Ultra-high-resolution imaging of intracranial flow diverters with photon counting CT: A comparative phantom study with flat-panel CT. 

Maurer CJ, Berlis A, Pinekenstein D, Wolf M, Östreicher G, Behrens L, Stangl FJ. Sci Rep. 2025 Jul 21;15(1):26498. doi: 10.1038/s41598-025-12713-0. PMID: 40691292

Middle Meningeal Artery Embolization for the Treatment of Chronic Subdural Hematomas-a German Nationwide Multi-center Study On 718 Embolizations. 

Vollherbst DF, Berlis A, Zaki M, Maurer C, Onyinzo C, Keil FC, Mann L, Arendt CT, Hartmann M, Reißberg S, Rutschke C, Kallenberg K, Grau S, Durutya A, Liebert A, Voit-Höhne HL, Holtmannspötter M, Herweh C, Chapot R, Elsharkawy M, Meila D, Greling B, Boxberg F, Grieb D, Deuschl C, Ahmadipour Y, Boeckh-Behrens T, Bodden J, Lukas C, Kämmerer F, Behme D, Diamandis E, Siebert E, Meddeb A, Kreiser K, Heinz S, Meckel S, Berzeg-Kolck S, Fiehler J, Bechstein M, Kaschner MG, Darvishi K, Leukert LS, Brockmann MA, Mayer TE, Buhk JH, Weyland CS, Görtz L, Kabbasch C, Weber W, Wendl C, Struffert T, Dyzmann C, Gerber JC, Bendszus M, Möhlenbruch MA. Clin Neuroradiol. 2025 Aug 18. doi: 10.1007/s00062-025-01549-w. Online ahead of print. PMID: 40824387 

Neutrophil Extracellular Traps and Delayed Cerebral Ischemia in Patients With Subarachnoid Hemorrhage. 

Schneider H, Münch D, Spalart V, Stroobants M, Berlis A, Maurer CJ, Jaschinski U, Kasner SE, Cao Q, Martinod K, Witsch J. J Am Heart Assoc. 2025 Oct 7;14(19):e041325. doi: 10.1161/JAHA.124.041325. Epub 2025 Sep 19. PMID: 40970545

Interdisciplinary neurovascular networks in Germany: update 2025. 

Wagner-Altendorf TA, Sieb K, Berlis A, Dörfler A, Mielke D, Groden C, Güresir E, Hamann GF, Jansen O, Meixensberger J, Müller O, Nabavi DG, Neumann-Haefelin T, Ossenbrink M, Regelsberger J, Royl G, Vatter H, Weber W, Werring N, Minnerup J, Röther J.Neurol Res Pract. 2025 Aug 22;7(1):59. doi: 10.1186/s42466-025-00418-8. PMID: 40847367

Role and Safety of Tirofiban in Peri-Interventional Antiplatelet Management for Aneurysm Treatment. 

Garayzade R, Berlis A, Arndt TT, Wolfert C, Sommer B, Müller G, Maurer CJ. Clin Neuroradiol. 2025 Jun;35(2):247-254. doi: 10.1007/s00062-024-01480-6. Epub 2024 Nov 28. PMID: 39607554

Results of an European survey on the management of perimesencephalic nonaneurysmal subarachnoid hemorrhage. 

Wolfert C, Sommer B, Krauss P, Mielke D, Maurer CJ, Berlis A, Raabe A, Shiban E. Sci Rep. 2025 Jul 8;15(1):24401. doi: 10.1038/s41598-025-06443-6. PMID: 40628816

Photon counting CT vs. flat-panel CT in the evaluation of enhancement patterns in chronic subdural hematoma after middle meningeal artery embolization. 

Maurer CJ, Behrens L, Schiele S, Zaki M, Quint G, Wolfert C, Sommer B, Stangl FJ, Berlis A. Front Neurol. 2025 May 16;16:1608308. doi: 10.3389/fneur.2025.1608308. eCollection 2025. PMID: 40452768

Long-term follow-up of patients with non-ischemic cerebral enhancing lesions following endovascular aneurysm treatment: magnetic resonance imaging findings, clinical course, and treatment. 

Ellssel M, Berlis A, Naumann M, Muthuraman M, Ding H, Schwarting S, Joachimski F, Maurer CJ, Bayas A. Ther Adv Neurol Disord. 2025 Jun 26;18:17562864251345650. doi: 10.1177/17562864251345650. eCollection 2025.PMID: 40584518

CLinical EValuation of WEB 17 device in intracranial aneuRysms (CLEVER): 1-year effectiveness results for ruptured and unruptured aneurysms. 

Spelle L, Costalat V, Caroff J, Wodarg F, Fischer S, Herbreteau D, Möhlenbruch MA, Januel AC, Papagiannaki C, Klisch J, Numminen J, Rautio R, Berlis A, Mihalea C, Chalumeau V, Downer J, Cortese J, Ikka L, Gallas S, Bester M, Liebig T, Velasco S, Grimaldi L, Byrne J, Szikora I, Pierot L, Cognard C. J Neurointerv Surg. 2025 Jul 14;17(8):878-882. doi: 10.1136/jnis-2024-021918. PMID: 38991733

In Vivo Discrimination of Iodine and Tantalum-Based Liquid Embolics After Intracranial or Spinal Embolization Using Photon-Counting Detector CT. 

Maurer CJ, Berlis A, Stangl FJ, Behrens L. Clin Neuroradiol. 2025 Sep;35(3):443-450. doi: 10.1007/s00062-025-01502-x. Epub 2025 Feb 6.PMID: 39915306

Upregulation versus loss of function of NTRK2 in 44 affected individuals leads to 2 distinct neurodevelopmental disorders. 

Berger E, Jauss RT, Ranells JD, Zonic E, von Wintzingerode L, Wilson A, Wagner J, Tuttle A, Thomas-Wilson A, Schulte B, Rabin R, Pappas J, Odgis JA, Muthaffar O, Mendez-Fadol A, Lynch M, Levy J, Lehalle D, Lake NJ, Krey I, Kozenko M, Knierim E, Jouret G, Jobanputra V, Isidor B, Hunt D, Hsieh TC, Holtz AM, Haack TB, Gold NB, Dunstheimer D, Donge M, Deb W, De La Rosa Poueriet KA, Danyel M, Christodoulou J, Chopra S, Callewaert B, Busche A, Brick L, Bigay BG, Arlt M, Anikar SS, Almohammal MN, Almanza D, Alhashem A, Bertoli-Avella A, Sticht H, Abou Jamra R. Genet Med. 2025 May;27(5):101326. doi: 10.1016/j.gim.2024.101326. Epub 2024 Nov 12. PMID: 39540377

Office Blood Pressure and Obesity in Children with X-Linked Hypophosphatemia. 

Böckmann I, Leifheit-Nestler M, Rehberg M, Spartà G, Evers K, Schlingmann KP, Kemper MJ, Richter-Unruh A, Hiort O, Grohmann-Held K, Derichs U, Freiberg C, Weitz M, Dunstheimer D, Schmid E, John-Kroegel U, Metzing O, Heger S, Jorch N, Staude H, Patzer L, Wühl E, Zivicnjak M, Schnabel D, Haffner D; German Society for Pediatric Nephrology (GPN) and the German Society for Pediatric and Adolescent Endocrinology and Diabetology (DGPAED). Calcif Tissue Int. 2025 Mar 28;116(1):56. doi: 10.1007/s00223-025-01363-z. PMID: 40152980

Growth dynamics of transversal body dimensions and proportions, with related clinical determinants in children with X-linked hypophosphatemia treated with phosphate supplements and active vitamin D. 

Brieger LC, Przygodda S, Bohlen AV, Rehberg M, Konrad M, Schlingmann KP, Hiort O, Schmidt D, John-Kroegel U, Wuehl E, Kemper MJ, Derichs U, Patzer L, Albers N, Dunstheimer D, Heger S, Grohmann-Held K, Schroeder C, Jorch N, Schmid E, Staude H, Weitz M, Freiberg C, Huebner A, Heitmeyer-Pyper A, Sparta G, Partsch CJ, Marx M, Land C, Baus I, Wilkening F, Moeller K, Simic-Schleicher G, Empting S, Metzing O, Wagner V, Holder M, Žebec MS, Schnabel D, Haffner D, Zivicnjak M; on behalf of; German Society for Pediatric Nephrology (GPN); German Society for Pediatric; Adolescent Endocrinology, Diabetology (DGKED). Pediatr Nephrol. 2025 Oct;40(10):3187-3200. doi: 10.1007/s00467-025-06841-y. Epub 2025 Jun 10. PMID: 40493262

Switch From rhPTH1-84 to TransCon PTH With Individual Dose Adjustment in Adult Hypoparathyroidism-4-Week Results. 

Siggelkow H, Peschke KA, Tsourdi E, Hofbauer LC, Berr CM, Hahner S, Lottspeich C, Schmidmaier R, Blaschke M. J Endocr Soc. 2025 Jun 30;9(9):bvaf113. doi: 10.1210/jendso/bvaf113. eCollection 2025 Sep. PMID: 40709359

Distinct pathways for genetic and epigenetic predisposition in familial and bilateral Wilms tumor. 

Wegert J, Appenzeller S, Treger TD, Streitenberger H, Ziegler B, Bausenwein S, Vokuhl C, Parks C, Jüttner E, Gramlich S, Ernestus K, Warman SW, Fuchs J, Hubertus J, von Schweinitz D, Fröhlich B, Jorch N, Knöfler R, Friedrich C, Corbacioglu S, Frühwald MC, Pekrun A, Schneider DT, Faber J, Stursberg J, Metzler M, Welter N, Pritchard-Jones K, Graf N, Furtwängler R, Behjati S, Gessler M. Genome Med. 2025 May 8;17(1):49. doi: 10.1186/s13073-025-01482-0. PMID: 40340749

An in vitro pharmacogenomic approach reveals subtype-specific therapeutic vulnerabilities in atypical teratoid/rhabdoid tumors (AT/RT). 

Pauck D, Picard D, Maue M, Taban K, Marquardt V, Blümel L, Bartl J, Qin N, Kubon N, Schöndorf D, Meyer FD, Theruvath J, Mitra S, Hasselblatt M, Frühwald MC, Reifenberger G, Remke M. Pharmacol Res. 2025 Mar;213:107660. doi: 10.1016/j.phrs.2025.107660. Epub 2025 Feb 16. PMID: 39961404

Developing an advanced risk stratification model for pediatric intracranial ependymoma based on the prospective trial E-HIT2000 and subsequent registries. 

von Hoff K, Obrecht-Sturm D, Ghasemi DR, Wenning J, Mynarek M, Gerber NU, Benesch M, Juhnke BO, Bison B, Warmuth-Metz M, Timmermann B, Faldum A, Tippelt S, Fleischhack G, Grotzer M, Driever PH, Beilken A, Ebinger M, Graf N, Frühwald MC, Schmid I, Slavc I, Koch A, Bergmann M, Hagel C, Coras R, Blümcke I, Reifenberger G, Felsberg J, Keyvani K, Harter PN, Prinz M, Staszewski O, Acker T, Stadelmann-Nessler C, Hartmann C, von Deimling A, Sommer C, Hasselblatt M, Riemenschneider MJ, Monoranu CM, Rushing E, Haberler C, Kool M, Sill M, Pfister SM, Schüller U, Pietsch T, Kortmann RD, Kwiecien R, Witt H, Pajtler KW, Rutkowski S; German, Austrian and Swiss HIT-Network. Neuro Oncol. 2025 Sep 30:noaf218. doi: 10.1093/neuonc/noaf218. Online ahead of print.PMID: 41026848

Malignant Rhabdoid Tumors of Cranial Nerves-A Clinically Distinct Group With Characteristic Neuroradiological, Histopathological, and Molecular Features. 

Gruhle M, Bison B, Gastberger K, Johann PD, von Lüttichau IT, Steinborn M, Tippelt S, Fleischhack G, Lehrnbecher T, Siebert R, Tüchert-Knoll SE, Melchior P, Vokuhl C, Hartmann W, Hasselblatt M, Frühwald MC. Pediatr Blood Cancer. 2025 Aug;72(8):e31823. doi: 10.1002/pbc.31823. Epub 2025 Jun 1. PMID: 40452127 

Malignant Rhabdoid Tumors of the Liver Are Associated With Inferior Outcomes Compared to Other Extracranial Rhabdoid Tumors. 

Bühner S, Gastberger K, Tüchert-Knoll S, Fincke VE, Johann PD, Melchior P, Teleshova M, Kachanov D, Shcherbakov A, Schmid I, Roka K, Siebert R, Vokuhl C, Gerss J, Fuchs J, Furtwängler R, Frühwald MC. Pediatr Blood Cancer. 2025 Dec;72(12):e32062. doi: 10.1002/pbc.32062. Epub 2025 Sep 19.PMID: 40974093 

Constitutional mosaicism of pathogenic variants in SMARCB1 in a subset of patients with sporadic rhabdoid tumors. 

Fleischmann LS, Nemes K, Glaser S, Kouroukli AG, Boros M, Bens S, Dahlum S, Kretzmer H, Oyen F, Gerss J, Hasselblatt M, Frühwald MC, Siebert R. Neuro Oncol. 2025 Feb 10;27(2):533-544. doi: 10.1093/neuonc/noae188. PMID: 39288268

A cycling, progenitor-like cell population at the base of atypical teratoid rhabdoid tumor subtype differentiation trajectories. 

Blanco-Carmona E, Paassen I, He J, DeMartino J, Büllesbach A, Anderson N, Buhl JL, Federico A, Mauermann M, Brok M, Straathof K, Behjati S, Vibhakar R, Donson AM, Foreman NK, Shaw M, Frühwald MC, Korshunov A, Hasselblatt M, Thomas C, Franke N, Kranendonk MEG, Hoving EW, Jäger N, Johann PD, Pfister SM, Filbin MG, Kool M, Drost J.Neuro Oncol. 2025 Dec 1;27(12):3260-3275. doi: 10.1093/neuonc/noaf179. PMID: 40726147

DICER1 Mutational Spectrum in Intracranial CNS-Neoplasias-A Review and a Report from the CNS-InterREST GPOH Study Center. 

Manea S, Fincke VE, Frühwald MC, Sturm D, von Zezschwitz B, Johann PD, Mucha M. Cancers (Basel). 2025 Apr 30;17(9):1513. doi: 10.3390/cancers17091513. PMID: 40361440

In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery. 

Riedel NC, Walter C, de Faria FW, Altendorf L, Aust P, Göbel C, Verma A, Ballast A, Bedzhov I, Roy R, Münter D, Schüftan E, Albert TK, Rössig C, Johann P, von Zezschwitz B, Sandmann S, Varghese J, Thomas C, Schüller U, Bruder JM, Kerl K. Cancer Commun (Lond). 2025 Dec;45(12):1670-1675. doi: 10.1002/cac2.70074. Epub 2025 Nov 2. PMID: 41177766

A rare case of atypical teratoid rhabdoid tumor (AT/RT) with homozygous SMARCB1 loss and one concurrent somatic heterozygous SMARCA4 variant. 

Müller Y, Bühner S, Fincke V, Mauch-Mücke K, Riemenschneider MJ, Manea S, Liesche-Starnecker F, Hasselblatt M, Dahlum S, Boros M, Siebert R, Frühwald MC, Johann P. Acta Neuropathol Commun. 2025 Oct 30;13(1):219. doi: 10.1186/s40478-025-02129-2. PMID: 41168858

Severe Asthma in Children and Adolescents: an AWMF Guideline by the German Society for Pediatric Pulmonology. 

Hamelmann E, Schorlemer C, Eber E, Gerstlauer M, Jung A, Kabesch M, Kopp MV, Lau S, Lex C, Möller A, Schaub B, Schwerk N, Spindler T, Taube C, Vogelberg C, Zacharasiewicz A, Zielen S, Schuster A, Gappa M. Klin Padiatr. 2026 Mar;238(2):65-73. doi: 10.1055/a-2752-7457. Epub 2025 Dec 23.PMID: 41435856

Targeting pediatric adrenocortical carcinoma: Molecular insights and emerging therapeutic strategies. 

Kuhlen M, Schmutz M, Kunstreich M, Redlich A, Claus R. Cancer Treat Rev. 2025 May;136:102942. doi: 10.1016/j.ctrv.2025.102942. Epub 2025 Apr 16. PMID: 40258305

Appendiceal neuroendocrine tumors in children and adolescents: The European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) diagnostic and therapeutic recommendations. 

Virgone C, Roganovic J, Rindi G, Kuhlen M, Jamsek J, Panagopoulou P, Bajciova V, Ben-Ami T, Raphael MF, Seitz G, Dall'Igna P, Terwisscha van Scheltinga SCEJ, Dierselhuis MP, Gorter RR, Bachiri S, Pape UF, Guérin F, Brecht IB, Fresneau B, Orbach D, Redlich A. Surgery. 2025 Aug;184:109451. doi: 10.1016/j.surg.2025.109451. Epub 2025 May 31. PMID: 40450811

Non-malignant features of cancer predisposition syndromes manifesting in childhood and adolescence: a guide for the general pediatrician. 

Kuhlen M, Weins AB, Stadler N, Angelova-Toshkina D, Frühwald MC. World J Pediatr. 2025 Feb;21(2):131-148. doi: 10.1007/s12519-024-00853-8. Epub 2024 Dec 6. PMID: 39641826

European clinical guidance for the management of adrenal and extra-adrenal paraganglioma in children and adolescents: a consensus by the EXPeRT group. 

Kuhlen M, Virgone C, Rigaud C, Irtan S, Casey R, Pamporaki C, Kunstreich M, Lopez-Almara R, Ben-Ami T, Bien E, Krawczyk MA, Mazic Cesen M, Ferrari A, Bisogno G, Reguerre Y, Abele M, Schneider DT, Fuchs J, Brecht IB, Timmermann B, de Krijger RR, Lapa C, Redlich A, Orbach D. Eur J Endocrinol. 2025 Nov 26;193(6):G13-G126. doi: 10.1093/ejendo/lvaf239. PMID: 41261973

Bridging molecular advancements and clinical challenges in pediatric oncology. 

Kuhlen M, Frühwald MC.World J Pediatr. 2025 Feb;21(2):120-122. doi: 10.1007/s12519-024-00870-7. PMID: 39695048

Pancreatic neuroendocrine tumors in children and adolescents-Data from the German MET studies (1997-2023). 

Karges K, Kunstreich M, Pape UF, Fuchs J, Vokuhl C, Abele M, Schneider DT, Brecht IB, Lapa C, Frühwald MC, Vorwerk P, Redlich A, Kuhlen M. J Neuroendocrinol. 2025 Aug;37(8):e70039. doi: 10.1111/jne.70039. Epub 2025 May 11. PMID: 40350184

Author Correction: International consensus statement on the diagnosis and management of phaeochromocytoma and paraganglioma in children and adolescents. 

Casey RT, Hendriks E, Deal C, Waguespack SG, Wiegering V, Redlich A, Akker S, Prasad R, Fassnacht M, Clifton-Bligh R, Amar L, Bornstein S, Canu L, Charmandari E, Chrisoulidou A, Freixes MC, de Krijger R, de Sanctis L, Fojo A, Ghia AJ, Huebner A, Kosmoliaptsis V, Kuhlen M, Raffaelli M, Lussey-Lepoutre C, Marks SD, Nilubol N, Parasiliti-Caprino M, Timmers HHJLM, Zietlow AL, Robledo M, Gimenez-Roqueplo AP, Grossman AB, Taïeb D, Maher ER, Lenders JWM, Eisenhofer G, Jimenez C, Pacak K, Pamporaki C. Nat Rev Endocrinol. 2025 Oct;21(10):656. doi: 10.1038/s41574-025-01167-z. PMID: 40804506 

Gastroenteropancreatic neuroendocrine neoplasms in children and adults: a comparative review. 

Kuhlen M, Claus R, Pavel ME, Kunstreich M, Begum N, Lapa C, Redlich A. Front Endocrinol (Lausanne). 2026 Jan 21;16:1736543. doi: 10.3389/fendo.2025.1736543. eCollection 2025. PMID: 41647110 

Artificial intelligence-based tools for precision diagnosis and treatment of neurofibromatosis type 1 associated peripheral and central glial tumors. 

Hellmann F, Ristow I, Well L, Lohse S, Anokhin M, Kuhlen M, André E, Harder A. Orphanet J Rare Dis. 2025 Oct 30;20(1):551. doi: 10.1186/s13023-025-04093-5. PMID: 41168866

Gastrointestinal Neuroendocrine Neoplasms in Children and Adolescents: Data from the German MET Studies (1997-2024). 

Karges K, Kunstreich M, Abele M, Fuchs J, Vokuhl C, Brecht IB, Schneider DT, Frühwald MC, Vorwerk P, Lapa C, Redlich A, Kuhlen M. Neuroendocrinology. 2025 Sep 25;116(1):1-12. doi: 10.1159/000548618. Online ahead of print. PMID: 40996947 

Delineating pediatric adrenocortical tumors by GC-MS urinary steroid metabolome analysis: observations from the MET study. 

Wudy SA, Pons-Kühnemann J, Kunstreich M, Redlich A, Hartmann MF, Kuhlen M. J Clin Endocrinol Metab. 2025 Nov 12:dgaf613. doi: 10.1210/clinem/dgaf613. Online ahead of print. PMID: 41225718 

Prolonged symptom duration and the potential for gradual progression in pediatric adrenocortical tumors: observations from the MET studies. 

Kuhlen M, Wudy SA, Baumann C, Vokuhl C, Hartmann MF, Kunstreich M, Claus R, Redlich A. J Pediatr Endocrinol Metab. 2025 Jun 30;38(9):931-938. doi: 10.1515/jpem-2025-0198. Print 2025 Sep 25. PMID: 40577853 

Interpretable Machine Learning Model for Survival Prediction in Pediatric Adrenocortical Tumors. 

Redlich A, Pfaehler E, Kunstreich M, Schmutz M, Slavetinsky C, Jüttner E, Holterhus PM, Warncke G, Vokuhl C, Fuchs J, Wudy SA, Kuhlen M. J Endocr Soc. 2025 Nov 18;10(2):bvaf177. doi: 10.1210/jendso/bvaf177. eCollection 2026 Feb. PMID: 41608202

Unveiling the Digital Evolution of Molecular Tumor Boards. 

Lutz S, D'Angelo A, Hammerl S, Schmutz M, Claus R, Fischer NM, Kramer F, Hammoud Z. Target Oncol. 2025 Jan;20(1):27-43. doi: 10.1007/s11523-024-01109-1. Epub 2024 Nov 28. PMID: 39609355

Large language model processing capabilities of ChatGPT 4.0 to generate molecular tumor board recommendations-a critical evaluation on real world data. 

Schmutz M, Sommer S, Sander J, Graumann D, Raffler J, Soto-Rey I, Sheikhalishahi S, Schmidt L, Unkelbach LP, Ortak L, Schaller T, Dintner S, Hildebrand K, Kuhlen M, Jordan F, Trepel M, Hinske C, Claus R. Oncologist. 2025 Oct 1;30(10):oyaf293. doi: 10.1093/oncolo/oyaf293. PMID: 40973166

Dissecting Tumor Heterogeneity by Liquid Biopsy-A Comparative Analysis of Post-Mortem Tissue and Pre-Mortem Liquid Biopsies in Solid Neoplasias. 

Mögele T, Hildebrand K, Sultan A, Sommer S, Rentschler L, Kling M, Sax I, Schlesner M, Märkl B, Trepel M, Schmutz M, Claus R. Int J Mol Sci. 2025 Aug 6;26(15):7614. doi: 10.3390/ijms26157614. PMID: 40806740

Artificial Intelligence Applications in Image-Based Diagnosis of Early Esophageal and Gastric Neoplasms. 

Ebigbo A, Messmann H, Lee SH. Gastroenterology. 2025 Aug;169(3):396-415.e2. doi: 10.1053/j.gastro.2025.01.253. Epub 2025 Mar 3.PMID: 40043857

Use of Endoflip - Impedance Planimetry System: For Which Indications? 

Nagl S, Ebigbo A, Messmann H.Visc Med. 2025 Jun;41(3):137-146. doi: 10.1159/000542545. Epub 2025 Jan 7. PMID: 40519765

Endoscopic Sustainability PrimAry Reporting Essentials (E-SPARE): European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. 

Cunha Neves JA, Baddeley R, Pohl H, Pioche M, Lorenzo-Zúñiga V, Albéniz Arbizu E, Mihai Voiosu A, Römmele C, Donnelly L, Elli L, Lopez-Muñoz P, Henniger D, Khalaf K, Bruno MJ, Arvanitakis M, Bisschops R, Hassan C, Messmann H, Gralnek IM, Siersema PD, Thomas-Gibson S, Hayee B, Rodriguez de Santiago E, Dinis-Ribeiro M. Endoscopy. 2025 Jun;57(6):674-688. doi: 10.1055/a-2543-0400. Epub 2025 Mar 20. PMID: 40112835

Per-oral endoscopic myotomy versus laparoscopic Heller's myotomy plus Dor fundoplication in patients with idiopathic achalasia: 5-year follow-up of a multicentre, randomised, open-label, non-inferiority trial. 

Hugova K, Mares J, Hakanson B, Repici A, von Rahden BHA, Bredenoord AJ, Bisschops R, Messmann H, Ruppenthal T, Mann O, Izbicki J, Harustiak T, Fumagalli Romario U, Rosati R, Germer CT, Schijven M, Emmermann A, von Renteln D, Dautel S, Fockens P, Boeckxstaens G, Rösch T, Martinek J, Werner YB. Lancet Gastroenterol Hepatol. 2025 May;10(5):431-441. doi: 10.1016/S2468-1253(25)00012-3. Epub 2025 Mar 17.PMID: 40112837

Curriculum for training in peroral endoscopic myotomy (POEM) in Europe (Part I): European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. 

Rodríguez de Santiago E, Tate DJ, Santos-Antunes J, Nagl S, Vacková Z, Tantau M, Araujo IK, de Moura EGH, Familiari P, Messmann H, Ebigbo A, Fockens P, Bisschops R, Heinrich H, Albéniz E, Sethi A, Kiosov O, Martinek J, Soetikno R, Gralnek IM, Tham TC.Endoscopy. 2025 Jul;57(7):778-795. doi: 10.1055/a-2568-7473. Epub 2025 Apr 9. PMID: 40203869

Curriculum for training in peroral endoscopic myotomy (POEM) in Europe (Part II) - Best Practice Techniques: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. 

Tate DJ, Rodriguez de Santiago E, Montori M, Lala V, Debels LK, Albéniz E, Araujo IK, de Moura EGH, Ebigbo A, Familiari P, Fockens P, Heinrich H, Kiosov O, Messmann H, Nagl S, Santos-Antunes J, Sethi A, Tantau M, Vackova Z, Martinek J, Soetikno RM, Gralnek IM, Tham TC. Endoscopy. 2025 Aug;57(8):912-941. doi: 10.1055/a-2569-7634. Epub 2025 May 28. PMID: 40436392

Computer-aided detection for esophageal achalasia (with video). 

Shiwaku H, Misawa M, Inoue H, Jiang K, Oda M, Familiari P, Costamagna G, Shimamura Y, Ikebuchi Y, Iwaya Y, Ominami M, Hayee B, Ho KY, So JBY, Htet HMT, Bhandari P, Grimes K, Messmann H, Colosso BMQ, Maselli R, Hassan C, Repici A, Stavropoulos SN, Fukami N, Bechara R, Kahaleh M, Sethi A, Beyna T, Neuhaus H, Chiu PWY, Santi EG, Sharma P, Eleftheriadis N, Minami H, Haber G, Draganov PV, Seewald S, Shiwaku A, Shiwaku Y, Mori K, Kudo SE, Hasegawa S. Dig Endosc. 2025 Aug;37(8):851-861. doi: 10.1111/den.15028. Epub 2025 Jun 12. PMID: 40506418 

Artificial Intelligence-assisted Endoscopy and Examiner Confidence: A Study on Human-Artificial Intelligence Interaction in Barrett's Esophagus (With Video). 

Roser D, Meinikheim M, Muzalyova A, Mendel R, Palm C, Probst A, Nagl S, Scheppach MW, Römmele C, Schnoy E, Parsa N, Byrne MF, Messmann H, Ebigbo A. DEN Open. 2025 Jun 19;6(1):e70150. doi: 10.1002/deo2.70150. eCollection 2026 Apr. PMID: 40548292

Use of artificial intelligence in submucosal vessel detection during third-space endoscopy. 

Scheppach MW, Mendel R, Muzalyova A, Rauber D, Probst A, Nagl S, Römmele C, Yip HC, Lau LHS, Gölder SK, Schmidt A, Kouladouros K, Abdelhafez M, Walter BM, Meinikheim M, Chiu PWY, Palm C, Messmann H, Ebigbo A. Endoscopy. 2025 Jul;57(7):760-766. doi: 10.1055/a-2534-1164. Epub 2025 Feb 5. PMID: 39909396 

The Legal and Ethical Framework for Artificial Intelligence in Gastrointestinal Endoscopy: A World Endoscopy Organization International Consensus Statement. 

Ahmad OF, Mori Y, Bretthauer M, Dourado DA, Hassan C, Bisschops R, Bhandari P, Byrne MF, Dekker E, Mahadevan U, May FP, Messmann H, Misawa M, Ogata H, Saito Y, Silverman AL, Wang P, Yano T, Aabakken L, Berzin TM. Ann Intern Med. 2026 Feb;179(2):270-275. doi: 10.7326/ANNALS-25-03415. Epub 2025 Dec 9. PMID: 41359967

International Validation of a Novel PEACE Scale to Improve the Quality of Upper Gastrointestinal Mucosal Inspection During Endoscopy. 

Romańczyk M, Desai M, Kamiński MF, Abe S, Alkandari AA, Beyna T, Bisschops R, Budzyń K, Bugdol M, Grover SC, Gyawali CP, Inoue H, Iyer PG, Messmann H, Ragunath K, Saito Y, Srinivasan S, Teshima C, Yadlapati R, Hassan C, Sharma P. Clin Transl Gastroenterol. 2025 Jan 1;16(1):e00786. doi: 10.14309/ctg.0000000000000786. PMID: 39853720

Langerhans Cell Histiocytosis of the Gastrointestinal Tract. 

Probst A, Kleinlein I, Messmann H. Clin Gastroenterol Hepatol. 2026 Mar;24(3):A23. doi: 10.1016/j.cgh.2025.04.010. Epub 2025 May 9. PMID: 40349888 

Severe gastroparesis complicated by gastric perforation caused by lightchain amyloidosis. 

Rietz M, Weber T, Schaller T, Luitjens JH, Uhrmacher L, Messmann H, Probst A. Z Gastroenterol. 2025 Apr;63(4):387-392. doi: 10.1055/a-2442-7944. Epub 2024 Nov 25. PMID: 39586808

Clinical evaluation of a novel single-use therapeutic gastroscope: a pilot feasibility study. 

Römmele C, Ayoub M, Wanzl J, Tadic V, Braun G, Weber T, Scheppach MW, Roser D, Matic K, Nagl S, Messmann H, Ebigbo A. Endoscopy. 2025 Apr;57(4):339-344. doi: 10.1055/a-2436-7933. Epub 2024 Oct 8. PMID: 39379048 

Correction: Curriculum for safe and effective use of artificial intelligence in endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. 

Mori Y, Kopylov U, Sinonquel P, Ebigbo A, Dekker E, De Groof AJ, Ahmad OF, Kader R, Saftoiu A, Schoon E, Mascagni P, Bhandari P, Hann A, Antonelli G, Iacucci M, Pech O, Dray X, Spadaccini M, Campion JR, Hassan C, Messmann H, Bisschops R, Fuccio L, Facciorusso A, Tham T. Endoscopy. 2026 Feb;58(2):C3. doi: 10.1055/a-2765-1088. Epub 2025 Dec 5. PMID: 41349574

Simulators and training models for diagnostic and therapeutic gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Technical and Technology Review. 

Coluccio C, Jacques J, Hritz I, Boskoski I, Abdelrahim M, Bove V, Cunha Neves JA, de Jonge PJF, Dell'Anna G, Esposito G, Facciorusso A, Gincul R, Giuffrida P, Kalapala R, Kapizioni C, Longcroft-Wheaton G, Nagl S, Tziatzios G, Voiosu T, Dray X, Barbieri B, Gralnek IM, Fuccio L. Endoscopy. 2025 Jul;57(7):796-813. doi: 10.1055/a-2569-7736. Epub 2025 Apr 4. PMID: 40185129

Feasibility, usability, and validity assessment of a novel plug-and-play virtual endoscopy simulator. 

Hohlstein P, Hollenbach M, Cahyadi O, Beck M, Bittel M, Dimitriadis S, Garbe J, Geissler ME, Heilani MW, Huber Y, Koch A, Kruse L, Mondorf A, Schlosser-Hupf S, Staudacher JJ, Welsch L, von Hahn T, Michael FA, Hamesch K; JuGa-Collaborators. Surg Endosc. 2026 Feb;40(2):1629-1640. doi: 10.1007/s00464-025-12396-8. Epub 2025 Dec 4. PMID: 41345533

Characterization of children with early onset pediatric multiple sclerosis. 

Kauth F, Bertolini A, Wendel EM, Koukou G, Naggar IE, Chung J, Baumann M, Schödl C, Lechner C, Bigi S, Blaschek A, Hengstler JG, Schimmel M, Nosadini M, Sartori S, Puthenparampil M, Van's Gravesande KS, Drenckhahn A, Nikolaus M, Kauffmann B, Thiels C, Häusler MG, Eckenweiler M, Karenfort M, Marina AD, Selek A, Öncel I, Kornek B, Reindl M, Rostásy K. Eur J Paediatr Neurol. 2025 Jan;54:113-120. doi: 10.1016/j.ejpn.2025.01.006. Epub 2025 Jan 23. PMID: 39879856 

Treatment response in children with relapsing MOG-antibody associated disease. 

Wendel EM, Chen JJ, Bertolini A, Blaschek A, Brilot F, Dale RC, Deiva K, Flanagan EP, Foiadelli T, Giorgi L, Huda S, Karenfort M, Kneen R, Lee V, Lim M, Mariotto S, Meirson H, Mohammed MZ, Nosadini M, Ramanathan S, Sartori S, Schimmel M, Shah VS, Thiels C, Tillema JM, Tomoum H, Wendel C, Schanda K, Reindl M, Rostasy K; BIOMARKER-Study group. Eur J Paediatr Neurol. 2025 Nov;59:45-51. doi: 10.1016/j.ejpn.2025.10.002. Epub 2025 Oct 10. PMID: 41092852 

A20 (TNFAIP3) Distinguishes Attack From Remission in Pediatric Patients With Monophasic MOGAD. 

Lechner C, Saxena S, Lokhande HA, Breu M, Eisenkölbl A, Karenfort M, Klein A, Leiz S, Preisel M, Rooney T, Rosso M, Schimmel M, Wendel EM, Reindl M, Baumann M, Rostasy K, Chitnis T.Neurol Neuroimmunol Neuroinflamm. 2025 Sep;12(5):e200452. doi: 10.1212/NXI.0000000000200452. Epub 2025 Aug 18. PMID: 40825157

Reduced brain volumes in children with radiologically isolated syndrome. 

Koukou G, Bartels F, Aigner A, Cleaveland R, Tuncer A, Wendel EM, Bertolini A, Wassmer E, Kornek B, Schimmel M, Panzer A, Finke C, Rostásy K. Mult Scler. 2025 Sep;31(10):1195-1204. doi: 10.1177/13524585251359066. Epub 2025 Jul 30. PMID: 40737451 

Corrigendum to "High association of MOG-IgG antibodies in children with bilateral optic neuritis" [Eur. J. Paediatr. Neurol. 27 (2020) 86-93]. 

Wendel EM, Baumann M, Barisic N, Blaschek A, de Oliveira Koch EC, Della Marina A, Diepold K, Hackenberg A, Hahn A, von Kalle T, Karenfort M, Kornek B, Lechner C, Leiz S, Merkenschlager A, Nosadini M, Schanda K, Schimmel M, Seemann L, Tüngler V, Waltz S, Wegener-Panzer A, Wiegand G, Reindl M, Rostásy K. Eur J Paediatr Neurol. 2025 Nov;59:119. doi: 10.1016/j.ejpn.2025.09.006. Epub 2025 Oct 9. PMID: 41073161

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Clinical Presentation and Course of Pulmonary Involvement in Chronic Nonbacterial Osteomyelitis. 

Hospach T, Blankenburg F, Heinkele A, Rücklová K, Müller-Abt P, Weller-Heinemann F, Buchtala L, Maier J, Kümmerle-Deschner J, Reiser C, Janda A, Urban A, Berendes R, Skrabl-Baumgartner A, Brunner J, Trauzeddel R, Haas JP, Holl-Wieden A, Morbach H, Schnabel A, Brück N, Hahn G, Emminger W, Valent I, Borchers R, Klemann C, Tsiflikas I, Klotsche J, Minden K, Hedrich CM, von Kalle T. ACR Open Rheumatol. 2025 Jan;7(1):e11799. doi: 10.1002/acr2.11799. PMID: 3987607

[Unclear cause of unilateral blindness with normal inflammation parameters]. 

Müller F, Pfob CH, Wahle M. Z Rheumatol. 2024 Dec;83(10):852-855. doi: 10.1007/s00393-024-01531-w. Epub 2024 Jun 14. PMID: 38874771

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Leucencephalopathy in Patients with Parkinson's Disease and Deep Brain Stimulation. 

Jarski P, Gasimov T, Dragaescu C, Sixel-Döring F, von Eckardstein K, Mollenhauer B, Trenkwalder C, Mielke D, Rohde V, Malinova V. Mov Disord Clin Pract. 2025 Mar;12(3):340-345. doi: 10.1002/mdc3.14294. Epub 2024 Dec 4.PMID: 39629747

Results of a German national survey to assess early mobilization versus bed rest in the postoperative management of incidental durotomy during lumbar surgery and the need for a randomized clinical trial. 

Abboud T, Asendorf T, Evangelou P, Younes B, Mielke D, Rohde V. Neurosurg Focus. 2025 Feb 1;58(2):E14. doi: 10.3171/2024.11.FOCUS24586. PMID: 39891938

Current state and future perspectives of spinal navigation and robotics-an AO spine survey. 

Motov S, Butenschoen VM, Krauss PE, Veeravagu A, Yoo KH, Stengel FC, Hejrati N, Stienen MN. Brain Spine. 2024 Dec 18;5:104165. doi: 10.1016/j.bas.2024.104165. eCollection 2025. PMID: 3981092

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• ADH-Mangel im Kindes- und Jugendalter (S1) – AWMF: 174-020 (September 2024) (Federführung)

• Atypische Teratoide / Rhabdoide Tumoren (S1) – AWMF: 025-037 (31.03.2024) (Mitarbeit)
• Leitsymptome und Diagnostik der ZNS-Tumoren im Kindes- Jugendalter (S1) – AWMF: 025-022 (02.06.2024) (Überarbeitung)
• Leitlinie chronische Schmerzstörung im Kindesalter (23.03.2026)

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• European clinical guidance for the management of adrenal and extra-adrenal paraganglioma in children and adolescents: a consensus by the EXPeRT group (Federführung)

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• VUR (Vesicoureteraler Reflux) (Mitarbeit)

• nn

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• SAMEDI (DeGIR/DGNR-Register)

• AQUAPE AGS
• AQUAPE Hypothyreose
• Insight-GHT-Register
• Hypoparathyreoidismus (Register und Biobank für Patient:innen mit Hypoparathyreoidismus) 

• ALL-BFM-Register
• AML-BFM 2017
• CESS-Register
• CML Paed II
• COSS
• CPT-SIOP-Register
• CWS-SoTiSar
• EU-RHAB
• EWING Register
• EWOG MDS 2006
• EWOG SAA
• GPOH HD-Register
• HIT-LOGGIC- Register
• HIT-REZ Register
• HLH 2004
• I-HIT MED Registry
• iHIT-HGG Registry
• INFORM
• KPS
• Kraniopharyngeom 2019 Register
• Lebertumorregister
• LOGGIC Core
• MET Register
• MNP Int-R
• NB Registry 2016
• NB with SCI
• NHL-BFM Registry 2012
• NPC-GPOH-2014-Register
• PTT 2.0
• Retinoblastomregister
• SoTiSaR 2.0
• STEP Register
• Umbrella SIOP-RTSG 2016
• Sichelzellregister
• Gephardregister
• DHR Hämophilie
• Register für seltene hämatologische Erkrankungen
• internes Tumorregister (alle onkolog. Neuerkrankungen, Rezidive und Zweitmalignome)
• DKKR (deutsches Kinderkrebsregister)

• Deutsches Mukoviszidose-Register
• GAN (German Asthma Net) -> schweres Asthma

• DBA-Register
• Register für Maligne Endokrine Tumoren (MET)
• Fanconi-Register
• KPS-Register
• Lokales Tumordatenmanagement (Dr. G. Schenkirsch)

• ESD-Register

• Epilepsie-Register
• SMArtCare
• GENERATE junior
• ESNEK
• NETRE

• ALS-Register Schwaben (Uniklinik Ulm)

• CureNet

•      LüRIgG-4, Registerstudie zu IgG4-assoziierter Erkrankung
•      Kerndokumentation rheumakranker Kinder und Jugendlicher
•      Pro-AID (Erweiterung ProKind Rheuma)

• Neocyst

• CCCA (Doku. aller HNO-Tumorpatienten)

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